Skip to content

Perspectives on Diabetes Care

This is the official blog of the Association of Diabetes Care & Education Specialists where we share recent research and professional opinions on diabetes care and education.


Explore Helpful Views on Diabetes Care & Education

If you're looking for professional opinions on diabetes care and education, you're in the right place. Perspectives on Diabetes Care is the official ADCES® diabetes care and education blog that shares helpful views on diabetes care and education. 

This is where you'll find practical tips on working with people affected by prediabetes, diabetes and related cardiometabolic conditions and the latest research and viewpoints on issues facing diabetes care and education specialists and the people they serve.



Current & Past ADCES Blog Articles


Identifying Key Components of Diabetic Retinopathy

Sep 28, 2016, 19:37 PM


e know that hyperglycemia leads to diabetic retinopathy, but research is still revealing exactly how it develops. I was intrigued to read about this recent study describing how high blood glucose switches genes to proteins in the eye. These proteins play a role in the development of retinopathy.

Dr. Michael Dennis and his colleagues found that the protein 4E-BP1 is higher in lab animals with diabetes. He compared mice with diabetes, with and without the protein, and its affect on vision loss. He found that the mice with diabetes who did not have the 4EBP1 protein did not have any vision loss. When drugs were used to lower blood glucose levels, they also saw a reduction in 4E-BP1 in the retina, suggesting a strong link.

When blood glucose is high, it prevents 4E-BP1 from being broken down. Identifying the 4E-BP1 protein helps inspire research to develop new therapies for diabetic retinopathy.

Maybe someday there will be medications specifically targeted to slow or prevent the progression of blindness due to diabetes.

Amy Campbell

About the Author

Amy Campbell is a dietitian and certified diabetes educator. She currently works in public health in Lexington, Kentucky and has been working in diabetes for over seven years.

View Bio & Previous Posts

Association of Diabetes Care & Education Specialists

Contact Us